Bollocks, injectable hgh should start binding to receptors almost immediately. It doesn't take a while to get going at all.
I'm not particularly arsed about missing out on natural hgh if i'm using synthetic hgh anyway, I'd inject 4-8iu and miss out on what... 0.5iu?... oh sh1t.... As far as i'm aware there's no proof that using synthetic hgh even affects natural production anyway is there?... ould be wrong but i've often heard it mentioned but never seen any evidence...
For me, best results from hgh were using pre cardio on a daily basis for fat loss (well 5 days a week as i had 2 off days) ... other than that i don't think it makes a blind bit of difference when you inject, muscular gains from hgh itself are minimal at best and timing of jabs is irrelevant in that respect ime.
"Bollox" Real inteligent. You state my post is Bollox and then kick of with "SHOULD" should do this should do that.
So what your really saying is you don't know! Is that the case?
Have a read at the link it should teach you something. Maybe! as for me IT DID TEACH ME.
You may not be arsed about shutting yourself down others are. http://jcem.endojournals..../content/full/85/2/601 "Exogenous 20K Growth Hormone (GH) Suppresses Endogenous 22K GH Secretion in Normal Men" Y. Hashimoto et al. 2000
It is of special interest since the experiment was done on 32 HEALTHY adults aged 20-31.
OK, the key findings which contradicts much of the hype around hgh:
*Exogenous hgh administration (sc) will not supress endogenous hgh production before 4 hours after administartion.
*IGF levels will raise slowly in 12 hours after administartion and then raise rapidly and reach a peak about 24 hours after administration.
*Exogenous hgh administration will supress endogenous hgh prduction for about 24 hours. This did even occur at small doses of 1-2iu a day.
*HGH is very dose dependant. A 10iu dose will give a ten fold increase in peak concentration levels of both hgh and igf-1. Also a bigger dose will not increase the supression time or peak times.
In regard to timining of hgh injections this would mean that the best time to inject your hgh is just before you go to sleep. That way you will still get your largest endogenous pulse, which accours about 2 hours after you go to sleep, and when that pulse is over, a little later in about 4 hours your hgh levelse will reach another peak from the hgh administration. The supression of your own hgh will be finished by the time you do your next injection the day after at the same time, so you will still get the deep sleep pulse the night after.
By taking your shots am you will supress all endogenous production of hgh the following nigth. Forget thinking that going up taking your shot 4am or 7am will help you not supress your own production, you will be shut down for 24 hours.
By doing several injections each day like am/afternoon you will shut down your own production completely.