Liver support on orals

 
wondered if anyone knew whether the way orals, say anavar is absorbed in the body can be counter-acted/reduced by liv support?
 
 

I think you will find that potential liver damage (long term/permanent) is massively overstated from oral AAS mainly through years of making assumptions of the wrong values from tests performed, having said that it wouldn't hurt to use something proven to help like Liv52 as a precaution as well as limiting cycles with orals AAS in them.
 
Bigfella.

Here are a couple of studies which looked at the liver damage from AAS
 
Anabolic steroid-induced hepatotoxicity: Is it overstated?

Clin J Sport Med 1999 Jan;9(1):34-9 (ISSN: 1050-642X)

Dickerman RD; Pertusi RM; Zachariah NY; Dufour DR; McConathy WJ

The Department of Biomedical Science, University of North Texas
Health Science Center, Fort Worth 76107-2699, USA.

OBJECTIVE: There have been numerous reports of hepatic dysfunction
secondary to anabolic steroid use based on elevated levels of serum
aminotransferases. This study was conducted to distinguish between
serum aminotransaminase elevations secondary to intense resistance
training and anabolic steroid-induced hepatotoxicity in elite
bodybuilders.

DESIGN: This was a case-control study of serum chemistry profiles
from bodybuilders using and not using anabolic steroids with
comparisons to a cohort of medical students and patients with
hepatitis.

PARTICIPANTS: The participants were bodybuilders taking self-
directed regimens of anabolic steroids (n = 15) and bodybuilders
not taking steroids (n = 10). Blood chemistry profiles from
patients with viral hepatitis (n = 49) and exercising and
nonexercising medical students (592) were used as controls.

MAIN OUTCOME MEASURES: The focus in blood chemistry profiles was
aspartate aminotransferase (AST), alanine aminotransferase (ALT),
gamma-glutamyltranspeptidase (GGT), and creatine kinase (CK)
levels.

RESULTS: In both groups of bodybuilders, CK, AST, and ALT were
elevated, whereas GGT remained in the normal range. In contrast,
patients with hepatitis had elevations of all three enzymes: ALT,
AST, and GGT. Creatine kinase (CK) was elevated in all exercising
groups. Patients with hepatitis were the only group in which a
correlation was found between aminotransferases and GGT.

CONCLUSION: Prior reports of anabolic steroid-induced
hepatotoxicity based on elevated aminotransferase levels may have
been overstated, because no exercising subjects, including steroid
users, demonstrated hepatic dysfunction based on GGT levels. Such
reports may have misled the medical community to emphasize steroid-
induced hepatotoxicity when interpreting elevated aminotransferase
levels and disregard muscle damage. For these reasons, when
evaluating hepatic function in cases of anabolic steroid therapy or
abuse, CK and GGT levels should be considered in addition to ALT
and AST levels as essential elements of the assessment.

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Evaluation of aminotransferase elevations in a bodybuilder using
anabolic steroids: hepatitis or rhabdomyolysis?
Pertusi R, Dickerman RD, McConathy WJ.
Department of Medicine, University of North Texas Health Science
Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107-2699, USA.
Abstract
The use of anabolic steroids among competitive athletes,
particularly bodybuilders, is widespread. Numerous reports have
noted "hepatic" dysfunction secondary to anabolic steroid use based
on elevated serum aminotransferase levels. The authors' objective
was to assess whether primary care physicians accurately
distinguish between anabolic steroid-induced hepatotoxicity and
serum aminotransferase elevations that are secondary to acute
rhabdomyolysis resulting from intense resistance training. Surveys
were sent to physicians listed as practicing family medicine or
sports medicine in the yellow pages of seven metropolitan areas.
Physicians were asked to provide a differential diagnosis for a 28-
year-old, anabolic steroid-using male bodybuilder with an abnormal
serum chemistry profile. The blood chemistries showed elevated
aspartate aminotransferase (AST), alanine aminotransferase (ALT),
and creatine kinase (CK) levels, and normal gamma-
glutamyltransferase (GGT) levels. In the physician survey (n = 84
responses), 56% failed to mention muscle damage or muscle disease
as a potential diagnosis, despite the markedly elevated CK level of
the patient. Sixty-three percent indicated liver disease as their
primary diagnosis despite normal GGT levels. Prior reports of
anabolic steroid-induced hepatotoxicity that were based on
aminotransferase elevations may have overstated the role of
anabolic steroids. Correspondingly, the medical community may have
been led to emphasize anabolic steroid-induced hepatotoxicity and
disregard muscle damage when interpreting elevated aminotransferase
levels. Therefore, when evaluating enzyme elevations in patients
who use anabolic steroids, physicians should consider the CK and
GGT levels as essential elements in distinguishing muscle damage
from liver damage.
Bigfella.

interesting read there BigFella - cheers
 
@ OP liver sups won't stop the absorption - you can always drink a glass of grapefruit which will bind to the enzyme CYP3A4 and stop the stomach from breaking the drug down before it gets to the liver - one glass a day will do

thank guys, good advice.