SHBG effects and how to reduce it for better gains on and off aas?

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stone14
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2008/06/07 11:16:05 (permalink)

SHBG effects and how to reduce it for better gains on and off aas?

ive been reading a thread on SHIC cycles and a guy (marcus300) mensioned SHBG effects which i think is interesting:
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marcus300
Basically SHBG is the body's way at maintaining homeostasis, testosterone weather its produced naturally or injected is either held in a "bound" or "free" state. What determines how much "free Test" is floating around our bodies so we can have benefits of building muscle tissue and all the other benefits of Test is SHBG (sex hormone binding globulin).

Studies have shown people with high levels of SHBG find it harder to build muscle than others, this is one of the reason why some bb'ers grow faster and quicker than others and seem to gain on alot on less gear. The more Test what is held in a "bound" state isn't working towards your goal, only the free testosterone is. This is why some who start to inject more test at a huge rate don't make anymore gains than on low dose, SHBG is producing more and holding what your injecting more of in a bound state, kinda pointless exercise.

Wise bodybuilders and top pro's know how to allow more free test be taken up by the cells rather than in a bound state rendering it useless, designing cycles and using compounds what attach to SHBG will allow more free test to flow. Notice how well gains are when you have a long time of gear? this is one of the reason's that a natural way of lowering SHBG.

Bloodwork has been taken on people who have been on test for a number of wks and its clearly shows the build up of SHBG which renders more test useless in a bound state, our own bodies system creating a homeostasis state, if your one of the many guys who class themselves has hard gainers this is one area were you should be looking and i am sure BW would clearly show how much free test is available and how much high levels of SHBG you have.

Certain compounds what attach itself to SHBG and certain natural remedies can help to free up more test.So careful planning of cycles is the key to great gains or better gains than you normally achieve, link all the issues together and create a very anabolic environment and you have cracked it to further muscle gains.
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some studies here:

http://SHBG/printout75.html

http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2265.1993.tb01769.x

http://www.lef.org/magazine/mag2000/jan00-cover2.html

http://jcem.endojournals.org/cgi/content/full/90/1/157

http://www.ironmagazine.com/printout75.html


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the main thread from page 4:
http://www.uk-muscle.co.uk/steroid-testosterone-information/32543-short-burst-cycling-explained-4.html


the thread from the beggining (if any1 wants to read):
http://www.uk-muscle.co.uk/steroid-testosterone-information/32543-short-burst-cycling-explained.html

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1)so i was just thinking would using prov be a good idea to some1 off aas to free up test from SHBG which finds it hard to gain naturally? assuming training, deit etc etc is sound.
(also i no there are some ppl who say prov will shut you down and some say it wont)

2)yes this may not be why they are finding it hard to gain natty but would it be werth while doing to see if it benifits them or not?


3)does anyone no of any natty remidies for inhibiting SHBG?

4)wherther you find it hard or easy to gain, inhinbiting the SHBG will benifit both types am i right?

5)does inhibiting estrogen also lower SHBG?

6)does inhibiting SHBG cause an increase in SHBG? as the body tries to even hormones out? which would be bad and therefore inhibiting SHBG as a natty bb pointless imo, correct?
post edited by stone14 - 2008/06/07 12:24:29

i believe with a healthy active lifestyle and some good knowledge and aas/peps use etc that you can live a longer stronger better life.

main interests: physique conditioning, bbj, muay thai.
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    stone14
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    RE: SHBG effects and how to reduce it? 2008/06/07 11:32:41 (permalink)
    also found this on proviron used on natty men: taken from this site http://www.sfd.pl/PROVIRON-t165979.html

    Here is the study I was referring to. Only 85 men out of 250 showed any suppression. Proviron did not shut down the HPTA in any of the subjects and that was at 150mg for 1 year. I would say its pretty safe and has very little effect on one's HPTA

    This study shows no effect on normal LH and FSH with 100-150mg/ d mesterolone, and decrease of FSH/LH that were elevated.

    Proviron doesn't substitute Clomid as hpta therapy, but doesn't get in the way, either.
    The effect of mesterolone on sperm count, on serum follicle stimulating hormone, luteinizing hormone, plasma testosterone and outcome in idiopathic oligospermic men.

    ............................................................................................................................

    so would its effects on SHBG be an advantage for a natty bb? yes i prov is an aas med but say if you dont wana be shut down, prov should help gains i think from what ive read, or am i wrong?
    post edited by stone14 - 2008/06/07 11:40:11

    i believe with a healthy active lifestyle and some good knowledge and aas/peps use etc that you can live a longer stronger better life.

    main interests: physique conditioning, bbj, muay thai.
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    stone14
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    RE: SHBG effects and how to reduce it? 2008/06/07 11:56:57 (permalink)
    hears more info on it, its a big article so i will just post the link:

    http://www.ironmagazine.com/article75.html

    here are some natty SHBG inhibitors it mensions, any1 heard of them?

    quote from article.
    1) Avena Sativa.
    One promising cure to the lack of "wake up wood" is the herb Avena Sativa. Users report a substantial increase in morning erections while using this product. Such a reaction suggests that Avena Sativa may actually reduce Sex Hormone Binding Globulin. Another anecdotal bit of evidence is the fact that some users complain of an outbreak of back acne. This, too, is a sign of an abrupt hormonal change not unlike what occurs during puberty or the beginning of a steroid cycle. The one drawback of Avena Sativa is that many commercial brands lack the active extract and it's the extract that makes it effective. When purchasing Avena Sativa, make sure it lists the percentage of "Avenacosides."

    It should be at least 5%. A daily dose of 500-1000 mgs may be just what you need to start the day off with a smile. Also, be aware of the old "bait and switch" tactic. There's one popular internet company that has used the active coside version of avena and naturally customers got good results. Then, they started putting the cheaper "non-coside" herbs into the formula. They even increased the total amount to make it look "new and improved" but of course more of the ineffective herb is meaningless. It's the cosides that count. The company in question even changed labels to "throw you off track." But coside percentages MUST BE STATED on the label. One product that has proven to contain the avenacosides in the correct dosage is "Unleashed" from www.proteinfactory.com


    2)
    Urtica Dioica.
    also known as Stinging Nettles, is an extremely interesting herb. It's not only been shown to reduce SHBG but it also lowers the female hormone prolactin. This is good news to anyone looking to stay lean and avoid the side effects of too much estrogen such as water retention and gynocemastia. Nettles has also been shown as an effective treatment for Benign Prostate Hypertrophy, due in part to the fact that it will suppress DHT (Dyhydrotestosterone). This is both good and bad. Although DHT is often referred to as the "bad" testosterone, it's also anabolic and necessary for libido and erectile function. So it may seem as if the use of Nettles may be working against your goals, but that's only if excessive dosages are used. (Over 500mgs a day)

    It is, however, a better choice for the treatment of an enlarged prostate than the more common application of Saw Palmetto which just blocks DHT but provides no benefit in terms of lowering estrogen or SHBG -- both of which are also a factor in prostate health. When testosterone isn't bio-available to the body, it can still impart its negative effects on the prostate. By reducing SHBG, prostate disorders can be avoided while increasing free testosterone and potential muscle growth.

    3)
    carao.
    From the jungles of Costa Rica comes a relatively new discovery -- to the western world at least. For years, the peasants living off the land have been using a unique medicine derived from the fruit of the Cassia Grandis plant.

    It's known as Carao and has been an effective natural remedy for anemia. But it also has an interesting side effect in many men. It spurs spontaneous erections! Could this be due to a lowering of SHBG? At this point, it would only be speculative to say. One would think that something that cured anemia would be high in iron but tests on Carao extract reveal almost no iron. This one is a big question mark. There are no official studies on Carao. It could be nothing more than the impoverished people were anemic before taking it and once cured, felt completely revitalized, yet among athletes who have tried it, the consensus is that it definitely improves endurance and sex drive. If you're especially adventurous and are willing to do some investigating in order to track it down, Carao may be just what you're looking for.

    There's a saying among the people who live in the small villages of Brazil: Until a man is 60, the child is his... after that, it's Catuaba. No, Catuaba isn't the town gigolo, it's an herb that has been used for centuries as a treatment for infertility. Studies are scant but one instance where Catuaba was administered to 100 men, it turned out that in more than half of them, sperm count increased while the weight of prostate decreased. This is tremendously exciting news to bodybuilders who want the most testosterone they can get without the potentially negative effects on the prostate.

    4)
    Muira Puama.
    is an exotic Amazon herb with rumored sexual enhancing properties that has been holding up to scientific scrutiny. Muira Puama was an ingredient in some of those "Anabolic Activators" from the early 90's which have fallen out of favor. Since the ingredients were based more on folklore than science, it was presumed there was little merit to such substances. Now medical research is bearing out what was just conjecture.

    There have been several scientific studies on the effects of Muira Puama and its ability to lower SHBG. It all began when French scientists conducted studies on the effects of the herb on rats. It turns out their rate of copulation doubled! Ensuing tests of humans brought about encouraging reports. More than half of the men tested with Muira Puama report heightened sex drive and the ability to maintain an erection longer. It's been popular among herbalists, but even many medical doctors have begun recommending it for erectile dysfunction and lack of libido. The theory behind its effectiveness is believed to be the release of bound testosterone.

    There are many versions of Muira Puama on the market, but as is the case with many herbal products, most of them contain little or no active sapions. When purchasing Muira Puama, make sure it contains the active extract. (Incidentally, "Unleashed" from Protein Factory.com also contains Muira Puama extract).




    post edited by stone14 - 2008/06/07 11:57:58

    i believe with a healthy active lifestyle and some good knowledge and aas/peps use etc that you can live a longer stronger better life.

    main interests: physique conditioning, bbj, muay thai.
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    stone14
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    RE: SHBG effects and how to reduce it for better gains on and off aas? 2008/06/07 20:06:31 (permalink)
    bump

    i believe with a healthy active lifestyle and some good knowledge and aas/peps use etc that you can live a longer stronger better life.

    main interests: physique conditioning, bbj, muay thai.
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