Can tren gyno be cured?

RE: Can tren gyno be cured? (dig)

Thu, 13 Dec 2007 19:39:53 GMT

ORIGINAL: squig

dig when you used the dostinex - did you use it while still on your cycle ? - and how long did you run it for /

squig

.

yeah because my gyno got really bad at the start of the cycle, i took it an carried on with the cycle with no further problems

i still, have some left as i didnt use once the pain had stopped.

RE: Can tren gyno be cured? (squig)

Thu, 13 Dec 2007 17:46:27 GMT

dig when you used the dostinex - did you use it while still on your cycle ? - and how long did you run it for /

squig

RE: Can tren gyno be cured? (macrophage)

Tue, 11 Dec 2007 22:38:19 GMT

GH presents its own issues since it can both directly agonize tissue as well as bind to the prolactin receptor.

basically if you have gyno, take care with GH use and if gyno presents cessation of use or reducing dosage is usually a good idea (at least while treating)

RE: Can tren gyno be cured? (drab4)

Tue, 11 Dec 2007 20:45:49 GMT

Interesting mate

GH is known for increasing prolactin levels.... So it appears that you did the right thing by adding an anti-prolacin....

http://www.ingentaconnect.com/content/ben/cnr/2007/00000004/00000001/art00002

RE: Can tren gyno be cured? (dig)

Tue, 11 Dec 2007 20:36:36 GMT

not wanting to get involved in this intillectual debate, its over my head, although it makes very good reading.

i can give my real life experience, i suffer badly from gyno on all courses and a while ago was running test,tren hGH for the first time, and my gyno got sore - as in very painful, not like the normal itchy kind i was used to. i stopped the test after only a few shots and the symptoms persisted. at this time i was panicking and taking tamoxifen at 100mg/day, sumtimes 140mg/day and it had absolutley zero effect.

i then got hold of cabeser and ran .5mg twice weekly and this totally cured my symptoms, compltley. i was never lactating at any point and i know the some test was prob still in my system, but to me it seemed to be caused by the combination of tren and hGH, and the cabeser seemed to be very effective.

just my 2 pence worth.

RE: Can tren gyno be cured? (drab4)

Tue, 11 Dec 2007 19:29:07 GMT

ORIGINAL: macrophage

progestins are NOT progesterone

Well no, of course not mate. Progesterone is one of many progestins, but not all progestins are progesterone! I was asking for a clarification of your views on the following statement:

"PgR most definitely affects both prolactin release, prolactin receptor expression and transcription."

PgR refers to the progesterone receptor as you know (some other members may not be aware of this of course). So your comments on either progesterone or other progestins would be interesting. In what way do you feel that the progesterone receptor is involved in prolactin release, prolactin receptor expression, and transcription?

Thanks

and given that nolva often causes a worsening of progestin related gyno its fair to assume increases release of prolactin.

As an aside, this is quite interesting. Are you saying that you think that tamoxifen increases the release of prolactin? Studies on this seem to indicate otherwise

Though obviously this varies, which is why some people can use nolva and effect improvement. the why one person has issues and another does not is likely related to PgR receptor isoforms, receptor densities as well as ER isoforms and receptor densities (though other factors may play into it as well).

Yes, I would agree that varying densities of ERa and b and PgRa and b will be influential in determining an individual's response to a wide variety of drugs. Some people seem practically immune to gyno, after all!

RE: Can tren gyno be cured? (macrophage)

Tue, 11 Dec 2007 18:46:58 GMT

ORIGINAL: drab4

ORIGINAL: macrophage

PgR most definitely affects both prolactin release, prolactin receptor expression and transcription.

Care to elaborate on this Macrophage?

As by "affects" one could easily mean "decreases" or "increases"

My reading on the subject (some years ago now so perhaps out of date) seemed to indicate that progesterone has a mild stimulatory effect on prolactin release in female animals, but the opposite in males

Cheers

progestins are NOT progesterone and given that nolva often causes a worsening of progestin related gyno its fair to assume increases release of prolactin.

Though obviously this varies, which is why some people can use nolva and effect improvement. the why one person has issues and another does not is likely related to PgR receptor isoforms, receptor densities as well as ER isoforms and receptor densities (though other factors may play into it as well).

RE: Can tren gyno be cured? (drab4)

Tue, 11 Dec 2007 15:31:30 GMT

ORIGINAL: macrophage

PgR most definitely affects both prolactin release, prolactin receptor expression and transcription.

Care to elaborate on this Macrophage?

As by "affects" one could easily mean "decreases" or "increases"

My reading on the subject (some years ago now so perhaps out of date) seemed to indicate that progesterone has a mild stimulatory effect on prolactin release in female animals, but the opposite in males

Cheers

RE: Can tren gyno be cured? (welshmatt983)

Tue, 11 Dec 2007 08:18:50 GMT

Using letro now at .5mg/day and also nolva 20mg/day, seems to be working a little. From what I've been told you put the letro under your tongue, leave for 10 secs then wash down with a drink yeah? Will move up to 1mg/day from next week see if that will work better

RE: Can tren gyno be cured? (macrophage)

Sat, 01 Dec 2007 19:53:18 GMT

ORIGINAL: PartyBoy

dostinex is an anti-prolactin, not an anti-progestin.

Prolactin is about as related to progestin as an apple is to an orange - that is they are both fruit!

yes and no. PgR most definitely affects both prolactin release, prolactin receptor expression and transcription. Suppression of prolactin is generally effective in treating and preventing gynecomastia from progestins like nandrolone and trenbolone.

So while cabaser is not an anti-progestin (though it does regulate both PgR and ER expression by suppressing prolactin) it is generally quite helpful with issues from progestins (also quite helpful with estrogenic issues- that can also stimulate prolactin release)

RE: Can tren gyno be cured? (jonnydenver)

Sat, 01 Dec 2007 17:20:12 GMT

From a compound that doesnt convert, you're either very unlucky or you're doing something wrong in your cycle..

RE: Can tren gyno be cured? (Papa Lazarou)

Sat, 01 Dec 2007 17:02:14 GMT

Personally without adex I get gyno with tren. If I get it 1mg ED for a few weeks kills my gyno dead in the water.

RE: Can tren gyno be cured? (welshmatt983)

Fri, 30 Nov 2007 22:21:36 GMT

how do I know if mine is fatty gyno or glandular? Mine are two small lumps behind both nipples about the size of large peas, not painfull at all. Been off AAS 3 months now, was hoping it would of cleared by now, gonna start my letro at .5mg per day then work up to maybe 2.5mg

RE: Can tren gyno be cured? (PartyBoy)

Sun, 25 Nov 2007 15:51:05 GMT

dostinex is an anti-prolactin, not an anti-progestin.

Prolactin is about as related to progestin as an apple is to an orange - that is they are both fruit!

RE: Can tren gyno be cured? (welshmatt983)

Sun, 25 Nov 2007 15:13:42 GMT

Think my source can only get letro from what im aware, I will try and get them all though as tamoxifen def aint working

RE: Can tren gyno be cured? (Aus~XXL)

Sun, 25 Nov 2007 14:38:05 GMT

you may also want to megadose vitamin 6. I didnt find it did much, but others recommend this for prog gyno.

Also AIFM direct onto nips may assist.

I used all 4 (letro, aifm, caber and selegiline) and over about 6 weeks I reversed it about 90% However, I had fatty gyno, not glandular.

Try to chemically treat it and im confident you will improve a lot. We all want to avoid surgery if possible but tbh it isn't the biggest deal in the world - many here have had it done incl. myself.

Keep reading up on the condition and how to treat it, take the above meds, and best of luck.

RE: Can tren gyno be cured? (welshmatt983)

Sun, 25 Nov 2007 13:49:19 GMT

Gyno is a growth (tumour) u cannot reverse it once u have one, u can keep it under control using anti E drugs. Surgery is the only way to remove it...... A guy I know said that to me, hope this letro and selegeline will do the trick, will have to wait n see!

RE: Can tren gyno be cured? (alistairh)

Sat, 17 Nov 2007 15:14:33 GMT

Ive had gyno fron deca when i was taking far to much ,I thought i had no chance of clearing it but it worked.

The faster you act the easier it is to kill.

RE: Can tren gyno be cured? (alistairh)

Sat, 17 Nov 2007 15:12:32 GMT

hi mate,
Try and get dostinex first to clear up the gyno and if you continue your cycle add a blocker throughout..

RE: Can tren gyno be cured? (welshmatt983)

Sat, 17 Nov 2007 15:08:12 GMT

will all these meds definatly clear it do you think? Or will they just for prevent it from getting worse?