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BLOOD PRESSURE MEDICINE OK WITH STEROIDS?? DANGERS DOC??

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figgy
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2005/07/29 06:27:39 (permalink)
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BLOOD PRESSURE MEDICINE OK WITH STEROIDS?? DANGERS DOC??

My doctor wants me to take ENALAPRIL at 5mg per day for high blood pressure....I want to know if I can still do a a steroid cycle while taking this medicine. I believe this medicine works on the receptors of the artery walls somwhow(I dont know the details).

Anyhow, Id like to do a PRIMOBOLAN/PROP(LOW DOSE) cycle and want to know if there are ANY DANGERS combinding ENALAPRIL with the steroids....
I appreciate your valuable time answering this question.......
#1

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    PartyBoy
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    RE: BLOOD PRESSURE MEDICINE OK WITH STEROIDS?? DANGERS DOC?? 2005/07/29 12:41:37 (permalink)
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    I can't say for sure whether there is any interaction, though to me it seems unlikely tbh, aside from the fact that steroids in general can give rise to elevated BP, thereby potentially worsening your hypertension.


    Here's some more info about the drug:

    Enalapril, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. Angiotensin is a vasopressor produced when renin is released from the kidney. Renin is formed by the juxtaglomerular apparatus of the kidney. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The beneficial effects of enalapril in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. Inhibition of ACE results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decreased aldosterone secretion. Although the latter decrease is small, it results in small increases of serum potassium. In hypertensive patients treated with enalapril alone for up to 48 weeks, mean increases in serum potassium of approximately 0.2 mEq/L were observed. In patients treated with enalapril plus a thiazide diuretic, there was essentially no change in serum potassium.

    #2
    n i n j a
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    RE: BLOOD PRESSURE MEDICINE OK WITH STEROIDS?? DANGERS DOC?? 2005/07/29 13:11:03 (permalink)
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    personally i would say that if you've got blood pressure that's high enough for your doctor to prescribe drugs to control it you really should be very careful about what steroids if any you chose to take.

    as said above most steroids will increase blood pressure thru water retention.

    ninja

    AKA theweeninjaguy.  8 st 2 lb when I joined this site, I’ve gained 7 stone + since then. 
    #3
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