RE: ECA stack for diabetic?
There are general side effects to Ephedrine which everyone needs to take into account ie blood pressure, heart rate etc.
In Medicine, prescribing ephedrine to a diabetic is not contraindicated but it is advised to do so with caution.
This is because it can affect blood glucose level control, usually increasing it.
Also when a diabetic has low blood glucose levels, ie a "hypo", which can be serious, they experience a set of symptoms such as Weakness,Drowsiness, Hunger, Confusion, Nervousness, Dizziness, Trembling, Rapid heartbeat, Sweating.
Many of the above symptoms are caused by the adrenaline that the adrenal glands release when hypoglycaemia occurs, to restore and maintain glucose levels in the blood. The adrenaline does this by mobilising stored glycogen from the liver and triglycerides from fat and converting them into glucose. Adrenaline also increases the secretion of glucagon and decreases the release of insulin.
Now side effects of Ephedrine are similar to Adrenaline, so there maybe some confusion if a diabetic is about to have a "hypo" or not. Thus more strict glucose monitoring maybe needed.
There is a separate thread in Diet forum regarding the effects of caffeine on glucose but this is less significant.