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IGF-1 whats the deal with it?

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THE BARBARIAN
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2005/07/22 12:24:54 (permalink)

IGF-1 whats the deal with it?

I see that there is now a link to muscle-research on the board, Iv herd that this is the real deal with IGf-1? and it works?

Iv been trying to research up on IGF-1 but im now very confused some people say its not worth it others say HGH is better, some claim it builds incredible muscle some claim it did nothing for them ect ect. I think there should be a sticky on the board by now.

Does this stuff actuall build muscle, i no GH is poor in this regurd?

The claim that got me interested was somebody who used it with a steroid cycle. He used it with tren and test and made gains in the range of 15lbs and kept it all post cycle! He said that when using just roids he commonly lost most of his gains post cycle even with good pct but when he added the IGF-1 LR3 he kept all his gains. He says thas what it does lets you keep your gains. Now iv done 3 roid cycles and on the first one i kept most of my gains but the two cycles i done after that i pritty much lost 100% of my gains from them, which ofcourse is very demoralising. Now i asked for advice and was told that my lost gains was likly due to my diet. Iv now got my diet sorted but i still worry that when i next do a cycle im just gonna loose every ounce again even with haveing good pct.
Is there any truth in that? will IGF-1 one help retain gains from roids in real world results? If so how is it best used with roids during a cycle and then post cycle to help retain gains.

cheers
#1

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    Play
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    RE: IGF-1 whats the deal with it? 2005/07/22 16:02:23 (permalink)
    IGF-1
    Insulin Like Growth Factor-1
    Drug Class: Growth Factor
    Dosage: 60-1000mcg daily
    Water Retention: Diet Dependant.

    IGF is naturally produced in the liver as a result of GH (growth hormone) metabolism in the presence of insulin. Muscle tissue can also produce IGF-1 by way of an intracellular response. In fact, one of the benefits of training sets that result in an intense burn , or stretch position training , is the production of natural IGF-1. It is also a side effect of oral 17-Alfa Alkylated steroids, which cause a higher release of IGF-1 from the liver. IGF-1 receptors exist throughout muscles and organs such as the heart, spleen, small intestines and kidneys with a higher concentration of receptors existing effects upon organs. IGF-1 is extremely anabolic, more so than GH or insulin.

    Recombinant IGF-1 (genetically engineered) was reported effective when injected intramusculary because it causes localized growth. This was the most popular method, and agreed the wisest for the most part.The drug has a half life of about ten minutes, and if it has been bound to IGF-BP3 (binding protein) the half life is extended to 12 hours. Pros often stack Insulin and or GH with IGF-1 because IGF-1 shuts off natural GH production and GH causes insulin resistance and interracts with Insulin. But this would actually be an untrue term for IGF-1.

    IGF-1 can have all the side effects of GH or insulin use with an added negative: Gastrointestinal growth. This is due to the high number of IGF-1 receptors in the GI tract as compared to skeletal muscle. The latter has more GH receptors. The explains much of the bloat of pro bodybuilders.

    IGF-1 is not stable in synthetic forms. A loud noise, shaking a vial and sudden heat changes can render it nothing more than expensive Amino Acids.Picture a piece of string folded up in a specific shape and held in that shape by a few fibers. This is what an amino acid sequence for GH or IGF-1 looks like,but the IGF-1 sequence has only 2 fibers keeping the active shape. The strand or string is a specific amino acid sequence. The shaping fibers holding the active shape are called disulfide bridges. Changing the folding or break a bridge and the IGF-1 no longer fits into it's receptor site. Like a key to a lock a drug must have the right shape to actuate it's receptor. Again this explains the necessity of careful preparation and site specific injection (into the musle group trained that day) when IGF-1 was administered.

    Common Stacks have been 0.25-0.50 of GH per KG of bodyweight stacked with 60-1000mcg of IGF-1 divided into 2-5 daily injections. Many have reported improved lean mass gains by combining both with insulin and high androgen AAS (d-bol, anadrol) for 4-8 weeks. Many simply injected 40-mcg of IGF-1 into the muscle group trained that day after training. It is important to note that IGF-1 can cause hypoglycemia and blood sugar monitoring is considered paramount.
    The reader should note that IGF-1 has been used clinically on children at dosages of over 3000-7000 mcg a day! No negative sides were reported though none were expected. The point being is that 40-100mcg of IGF-1 used by athletes is most likely insufficient yet very expensive, However the results some individuals have realized through IGF-1 have been amazing
    #2
    drab4
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    RE: IGF-1 whats the deal with it? 2005/07/22 17:06:33 (permalink)
    There are no studies on long R3 IGF in humans.

    The stuff is anabolic in cattle and rats. But catabolic in pigs.

    People who use it report VERY variable results. Some love it, some think it's total crap.

    I'd prefer to use GH personally as it has studies in humans and it definately has some effect.
    #3
    khany
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    RE: IGF-1 whats the deal with it? 2005/07/22 17:49:47 (permalink)

    ORIGINAL: THE BARBARIAN

    I see that there is now a link to muscle-research on the board, Iv herd that this is the real deal with IGf-1? and it works?

    Iv been trying to research up on IGF-1 but im now very confused some people say its not worth it others say HGH is better, some claim it builds incredible muscle some claim it did nothing for them ect ect. I think there should be a sticky on the board by now.

    Does this stuff actuall build muscle, i no GH is poor in this regurd?

    The claim that got me interested was somebody who used it with a steroid cycle. He used it with tren and test and made gains in the range of 15lbs and kept it all post cycle! He said that when using just roids he commonly lost most of his gains post cycle even with good pct but when he added the IGF-1 LR3 he kept all his gains. He says thas what it does lets you keep your gains. Now iv done 3 roid cycles and on the first one i kept most of my gains but the two cycles i done after that i pritty much lost 100% of my gains from them, which ofcourse is very demoralising. Now i asked for advice and was told that my lost gains was likly due to my diet. Iv now got my diet sorted but i still worry that when i next do a cycle im just gonna loose every ounce again even with haveing good pct.
    Is there any truth in that? will IGF-1 one help retain gains from roids in real world results? If so how is it best used with roids during a cycle and then post cycle to help retain gains.

    cheers


    one of the MODs who also competes on a board i MOD uses IGF in PCT and says he vertualy keeps 100% of his gains
    #4
    POWERHOUSE585
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    RE: IGF-1 whats the deal with it? 2005/07/22 18:18:24 (permalink)
    as my man drab says some like it some dnt
    there are many non responders also
    i for one experiance great strength increase and increased appetite with it
    i like it and its keep me full and pretty low bf while also gaining small amounts
    will have to try it for the whole ov this year to give exact reuslts
    #5
    POWERHOUSE585
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    RE: IGF-1 whats the deal with it? 2005/07/22 18:19:22 (permalink)
    ah yes and if u are a good responder it is a great med for pct
    with some and even me gainin a lb or two while off
    #6
    THE BARBARIAN
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    RE: IGF-1 whats the deal with it? 2005/07/22 22:03:20 (permalink)
    The thing is iv read the reports on many other boards where guys ran this stuff for as little as 25 days yet seen an increase in muscle mass of around 5 to 8lbs and this gain was pure muscle 100% kept when they finished. They say after 30 days it becomes ineffective and you need a break of a few months then back on again and repeat. If this is the case and you can gain even as little as 5lbs of pure muscle in a month on this stuff and do this 3 or 4 times year, then the point in using steroids is what? The dose was only 50mcg for one guy and he claims 8lbs of lean mass in 4 weeks, Said it was very protein dependant tho and you need in the range of 400grams per day to see this result. And he claims he lost bodyfat as well.
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    THE BARBARIAN
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    rickster
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    RE: IGF-1 whats the deal with it? 2006/04/11 16:21:26 (permalink)
    is igf-1 the same if in pill form, im assuing i still need to take into consideration my weight as well during hgh cycle with aas
    #9
    rickster
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    RE: IGF-1 whats the deal with it? 2006/04/11 16:45:02 (permalink)
    starting my second course of hgh (4iu ed 4 on 2 off)

    i will be consumin 6 meals prodomiinantely protein and shakes throughout the day splitting my training into muscle groups of chest and triceps/back and biceps/shoulders/legs and abs.

    ive heard a lot about igf-1 with hgh do you get much more of a gain for takng it guys?

    if so assuming its dependent on how heavy u are!!

    aiming to eat 300g protein, 600g carbs, 50g fat is that sufficient?

    ive been told its good to eat straight after hgh inj but have read to take inj hour before or after eating, DYOU GUYS KNOW ??????
    #10
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