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Mk-677 JW Supplements

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Gym Gorilla
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2015/01/22 11:51:08 (permalink)
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Mk-677 JW Supplements

Hi all, I've been interested in this for quite some time and have now noticed JW supplements are stocking it at 10mg per tablet.

I just wondered how effective the tablet version would be as opposed to the liquid droppers out there?


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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 12:11:40 (permalink)
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    It would have to be taken in relatively high doses (hence the Mg dosing) and desensitization will occur meaning one has to increase the dose as one progresses.
    It works, but Injectable GHRPs and ModGRF(1-29) are more cost effective.
     
    MK-677 Ibutamoren  is not a bad option for the needle shy though and it has a longer lasting action than the Peptides.
     
    So if you can afford to run it its worth a go. 
    The same cautions that are required when using Exogenous HGH should be observed due to MK-677 long lasting action. 
    post edited by Dumbat - 2015/01/22 12:15:11

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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 12:28:39 (permalink)
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    Thanks for the speedy response.

    It's going for £55 for 90 x 10mg tabs, seems pretty cheap compared to some of the 25mg per ml / 30ml dropper bottles I've seen so i was a bit wary of its bioavailability being a tablet?

    It's something I was interested in using out of convenience rather than using multiple peptides, reconstituting / multiple injections.

    I've seen cycles of 25mg a day as a recommended minimal dosage, how long do you think you could run before desensitazion occurs?

    Thanks


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    Uriel
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    Re: Mk-677 JW Supplements 2015/01/22 12:30:02 (permalink)
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    Was looking into it earlier and it's not cost effective. One guy posted blood work on this stuff, and on 25mg a day he was barely off range on GH and IGF-1. It's high but not really that high, probably not enough to make any real gains.
     
    Realistically you'd probably need to use this stuff at more like 50mg a day to warrant calling it an anabolic. That's gonna cost you as much as using a low dose of actual HGH or a ****load of GHRP-2.
     
    It'll be worth a shot when some cheaper, higher dosed clones come out (are you listening bodyconscious?).
    post edited by Uriel - 2015/01/22 12:31:35
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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 12:35:55 (permalink)
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    ^^^^ Yes:
    Injectables will always be more efficient, so if you are happy injecting yourself then this is the better option.
     
    Personally I will always take the injectable option on anything. 
    Recent research has encouraged another look at CJC with DAC. It is now considered to be viable for a more continuous HGH release. Although as I stated before caution needs to exercised when using anything that increases systemic IGF for long periods of time; the risk of cancerous tumour trophy for one.  
    A pulsative action is always more desirable and safer.
    post edited by Dumbat - 2015/01/22 12:40:49

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    Uriel
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    Re: Mk-677 JW Supplements 2015/01/22 12:48:20 (permalink)
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    Going slightly off topic, but everyone always assumes you need a GHRH with your GHRP, but you kinda don't. GHRPs stimulate GH production all by themselves. Not as much, but considering that GHRHs generally cost over 5x as much per mg as GHRPs, I'm not sure you'll actually get more total GH produced at the end of the day from using the combo shot rather than just more shots of GHRP alone.
     
    GHRP-2 by itself is dirt cheap. Gonna give it a trial solo run some day.
    post edited by Uriel - 2015/01/22 12:51:06
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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 13:01:50 (permalink)
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    Uriel:
    Yes you will get a release of endogenous HGH but only a very small amount.
    The combination of  a GHRP and a GHRH has a synergistic effect. ( 2+2 = 7 ) 
    You are likely to be disappointed  if you plan to use a GHRP on its own. 

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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 13:03:51 (permalink)
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    Using a lower amount of both GHRP and GHRH , less than saturation dose, will still give a greater release of Endogenous HGH .
     

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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 13:09:04 (permalink)
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    Thanks for the info guys.

    So if I were to run peptides instead, what would you recommend as the simplest possible daily dosages for a first time peptide user?

    I was considering tablet form to avoid constant pinning etc having gotten bored to tears pinning on previous conventional cycles


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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 13:09:04 (permalink)
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    Thanks for the info guys.

    So if I were to run peptides instead, what would you recommend as the simplest possible daily dosages for a first time peptide user?

    I was considering tablet form to avoid constant pinning etc having gotten bored to tears pinning on previous conventional cycles


    "eat, lift, live, BIG"
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    Uriel
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    Re: Mk-677 JW Supplements 2015/01/22 13:11:03 (permalink)
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    Dumbat
    Uriel:
    Yes you will get a release of endogenous HGH but only a very small amount.
    The combination of  a GHRP and a GHRH has a synergistic effect. ( 2+2 = 7 ) 
    You are likely to be disappointed  if you plan to use a GHRP on its own. 


    From what I've been reading adding GHRH at a 1:1 ratio roughly doubles the GH output:

     
    The thing is, I just ran some quick numbers and one shot of 200mcg GHRP-2 and Mod-GRF each costs me about the same as 5 shots of 200mcg of GHRP-2 alone. Even if I only get half as much GH per pulse, at the end of the day I can get 2.5x as much total GH released for the same money. I just have to poke myslef full of holes.
     
    There also seems to be some new data on the whole saturation thing and while there are diminished returns there doesn't really seem to be a cut off dose for GHRP-2, the more you use the more GH you get. Supposedly some guys are dosing 1000mcg per shot, 3 times a day and getting GH levels comparable to ~8IUs of exogenous HGH.
    post edited by Uriel - 2015/01/22 13:13:54
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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 13:31:51 (permalink)
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    There is not a cut off point as such, but it is a process of diminishing returns.
    Athough there is only so much growth factor that the Pituitary gland can produce.
    Direct comparisons to  exogenous HGH are only of limited value as Endogenous "HGH" has many different actions and the Pulsative release also  results in different effects.
    For the best reliable information on these Peptides Datbtrue.co.uk is the site to go to.
    I respect the site too much to simply copy and paste from there but this comparison is explained.
    I will try and find the relevant thread. 
    If there was no requirement for ModGRF(1-29) no one would use it. 
    post edited by Dumbat - 2015/01/22 14:12:19

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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 13:37:43 (permalink)
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    To the O.P I am not a great fan of wiki but there is some relevant information here:
     
     http://en.wikipedia.org/wiki/Ibutamoren
     

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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 14:12:36 (permalink)
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    Apologises dumbat, I meant if I were to use ghrp2 instead of ibutamoren, what would be the most simplistic and beneficial dosage protocol for a first time peptide user? It's put me off before because of all the faffing involved haha.

    Again much appreciated.


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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 14:12:36 (permalink)
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    Apologises dumbat, I meant if I were to use ghrp2 instead of ibutamoren, what would be the most simplistic and beneficial dosage protocol for a first time peptide user? It's put me off before because of all the faffing involved haha.

    Again much appreciated.


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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 14:15:46 (permalink)
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    Take a look at my reply in this thread:
    http://www.muscletalk.co....ly-cycle-m5259492.aspx

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    simonboyle
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    Re: Mk-677 JW Supplements 2015/01/22 16:00:56 (permalink)
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    Thread went off topic rather quick
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    Dumbat
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    Re: Mk-677 JW Supplements 2015/01/22 16:51:19 (permalink)
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    Not really, still endogenous growth hormone related. 
    This is how discussion is developed.
    No one has said that MK-677 isn`t effective , we are simply explaining the pros and cons to the O.P. 

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    Gym Gorilla
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    Re: Mk-677 JW Supplements 2015/01/22 16:56:17 (permalink)
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    Dumbat you're a superstar, Great help.

    Realistically and I'm just playing devils advocate here, what do you think would be more beneficial, ghrp2 stand alone at 300mcg a day or mk677 at 25mg per day.

    I really want to keep things as basic as possible + I know adding mod would increase GH levels more but Id like to keep cycles as simple as possible.

    Thanks for all your help mate.


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    huxley
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    Re: Mk-677 JW Supplements 2015/01/22 17:53:05 (permalink)
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    You'll need to run 50mg of mk667 for it to be decently effective, a £50 bottle would last me just two weeks so no it's far from cheap.
     
    Was it effective, for me i noticed some leaning out, i felt fuller skin was clearer and brighter, and sleep improved.
     
    Honestly i'd rather pop 100mg 5-htp each night, as ibutamorem is pricey.
     
    Have a look at russianstar he's done a lot of logs on it iirc.
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