Personally I do not believe the Receptor saturation theory.
Gains will slow down as one progresses, look at the top professional BBers, a gain of 5 lbs of LBM in a year is considered good for them.
While we do overcome some of our genetic limits through AAS use there are still factors that will limit the amount of muscle mass that we can obtain and maintain.
Growth is an exponential process with gains becoming exponentially less as AAS use has to become exponentially greater.
(More for less)
Going "natty" will only result in loss of mass , you would still have to run high doses of AAS to get to your goals.
As for the appearance issue, yes the changes will be less noticeable as one progresses as the gains will be proportionally less ( a lower percentage of what one already has)
The addition of other compounds can help, HGH, Peptides, insulin etc.
post edited by Dumbat - 2015/01/03 13:05:24