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glutamine: free form or peptide?

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Daari
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2004/02/19 00:00:03 (permalink)
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glutamine: free form or peptide?

I always thought that these two where indeed the same thing, but after reading various articles on the net apparantly 65% of the free form glutamine is not transported to muscles, but all the peptide bonded glutamine is (absorbed via different mechanism). Can anyone please shed some light on this, is this for real or is it a marketing hype?

thanks

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    James
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    RE: glutamine: free form or peptide? 2004/02/19 10:08:19 (permalink)
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    they are different, though I dont know how they came up with 65%.

    I have outlined the different mechanisms in my article in this newsletter here http://www.muscletalk.co.uk/newsletter-0303.asp
    pop
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    RE: glutamine: free form or peptide? 2004/02/19 12:52:06 (permalink)
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    I believe there are studies showing that l-glutamine taken oraly is mostly destroyed in the gut, or used in the glycusomosis (sp?) process, and is therefore just a waste.

    Manufacturers of new products like "G-plenish" claim to be more sucessfull at reaching the intended muscles etc.

    James
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    RE: glutamine: free form or peptide? 2004/02/19 13:11:24 (permalink)
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    I know you may have spelt it wrong, but I have never come across anything like the term glycusomosis before. What is it?

    Gln taken orally is treated like any other amino acid, so I would like to see those studies, as they imply what we eat from food is also mostly destroyed.
    Daari
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    RE: glutamine: free form or peptide? 2004/02/19 18:59:45 (permalink)
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    SO do u rekon it's worth me paying an extra tenner for a kilo of peptide bonded glutamine?
    Boxer
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    RE: glutamine: free form or peptide? 2004/02/19 20:57:44 (permalink)
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    quote:
    Originally posted by Adil

    SO do u rekon it's worth me paying an extra tenner for a kilo of peptide bonded glutamine?


    No, go for the free form if you must buy glutamine.
    Daari
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    RE: glutamine: free form or peptide? 2004/02/19 20:59:57 (permalink)
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    thats what i'm on right now-i'm gonna stop taking it soon and increase my whey intake by around 20g a day to see if it makes any difference
    pop
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    RE: glutamine: free form or peptide? 2004/02/19 21:49:29 (permalink)
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    quote:
    Originally posted by James

    I know you may have spelt it wrong, but I have never come across anything like the term glycusomosis before. What is it?

    Gln taken orally is treated like any other amino acid, so I would like to see those studies, as they imply what we eat from food is also mostly destroyed.



    James, take a look at this:

    http://forum.bodybuilding.com/showthread.php?s=&threadid=196615&highlight=glutamine

    http://www20.uludag.edu.tr/%7Ehakan/sbtd/vol2/n4/7/v2n4-7.htm
    pop
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    RE: glutamine: free form or peptide? 2004/02/19 22:13:26 (permalink)
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    quote:
    Originally posted by James

    I know you may have spelt it wrong, but I have never come across anything like the term glycusomosis before. What is it?




    Taken from the last post on page 2, by "Bobo"

    "Your body would rather use glutamine as a fuel source (through gluconeogenisis) in times of a caloric deficit. It could help in reducing catabolism just by the fact its used as a fuel but I don't think people want to buy it if they know its just going to turned into glucose eventually. Expenisive glucose in this case "
    James
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    RE: glutamine: free form or peptide? 2004/02/20 14:43:23 (permalink)
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    Did you mean gluconeogenesis (GNG) rather than glycusomosis then? if so - then you can see why I was confused

    I have debated many times about gln here and people omit its main useful point (why it is used in the ITU setting), inthat gln itself is the preferred source of fuel for enterocytes (intestinal cells), ie it helps them function to absorb nutrition better.

    So Bobo has a point that gln is used in GNG in the enterocytes. The equation is alot more complex then 'it just gets turned into glucose.
    pop
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    RE: glutamine: free form or peptide? 2004/02/20 20:58:52 (permalink)
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    quote:
    Originally posted by James

    Did you mean gluconeogenesis (GNG) rather than glycusomosis then? if so - then you can see why I was confused




    Yes, I meant gluconeogenesis, but bio-chem aint my strongest subject!
    stan
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    RE: glutamine: free form or peptide? 2004/06/10 17:29:00 (permalink)
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    I cant seem to find the peptide version in the UK........

    .......on a side not - the UK is a rip off.....everything is so much more expensive than in the states. Go to an american supplement company and look at the prices - you will be disgusted.
    T-Bone123
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    RE: glutamine: free form or peptide? 2004/06/10 18:31:51 (permalink)
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    quote:
    Originally posted by stan

    I cant seem to find the peptide version in the UK........

    .......on a side not - the UK is a rip off.....everything is so much more expensive than in the states. Go to an american supplement company and look at the prices - you will be disgusted.



    Yes but there are reasons for this - economies of scale in the USA relative to the UK and a weak dollar/strong pound combination which favours imports.
    It is frustrating mate but we have to remember that UK retailers are probably not benefitting from any higher margins than their USA counterparts.
    Daari
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    RE: glutamine: free form or peptide? 2004/06/10 18:36:24 (permalink)
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    www.phoenixathletic.com look for the brand name 'SNI'
    langers
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    RE: glutamine: free form or peptide? 2004/06/10 19:23:43 (permalink)
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    quote:
    Originally posted by T-Bone123

    quote:
    Originally posted by stan

    I cant seem to find the peptide version in the UK........

    .......on a side not - the UK is a rip off.....everything is so much more expensive than in the states. Go to an american supplement company and look at the prices - you will be disgusted.



    Yes but there are reasons for this - economies of scale in the USA relative to the UK and a weak dollar/strong pound combination which favours imports.
    It is frustrating mate but we have to remember that UK retailers are probably not benefitting from any higher margins than their USA counterparts.




    well said that man.
    ham
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    RE: glutamine: free form or peptide? 2004/06/10 22:17:27 (permalink)
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    newcomer: N acetyl glutamine
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